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. 2019 Jul 22;9:10573. doi: 10.1038/s41598-019-45866-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Isoprenoid synthesis genes down-regulated in rice roots colonised by H. seropedicae. The names of the genes differentially expressed are shown and the numbers in parentheses represent the fold change. The components of the MEP pathway leading to geranylgeranyl diphosphate synthesis and the diterpenoid- phytoalexin pathway are: G3P, glyceraldehyde-3-phosphate; DXP, 1-deoxy-D-xylulose 5-phosphate; MEP, 2-C-methyl-D-erythritol 4-phosphate; CDP-ME, 4-(cytidine 5-diphospho)-2-C-methyl-D-erythritol; CDP-ME2P, 2-phospho-4-(cytidine 5′-diphospho)-2-C-methyl-D-erythritol; MEC-DP, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; HMBDP, 1-hydroxy-2-methyl-2-butenyl 4-diphosphate; IPP, isopentenyl diphosphate; DMAPP, dimethylallyl diphosphate; GGDP, geranylgeranyl diphosphate; and CDP, copalyl diphosphate. Enzymes are indicated in rose coloured circles: DXS, 1-deoxy-D-xylulose 5-phosphate synthase; DXR, DXP reductoisomerase; CMS, CDP-ME synthase; CMK, CDP-ME kinase; MCS, MECDP synthase; HDS, HMBDP synthase; HDR, HMBDP reductase; IPI, IPP isomerase; GGPS, GGDP synthase; OsCyc1, syn-CDP synthase; OsCyc2, ent-CDP synthase; OsDTC2, stemar-13-ene synthase.