Table 3.
Planned and delivered dose results based on normalized 99mTc-MAA SPECT and 90Y-microsphere PET respectively
Normalized 99mTc-MAA SPECT Mean ± SD |
90Y-MS PET Mean ± SD |
Bias [95% CI] | Pearson’s correlation | |
---|---|---|---|---|
DT (Gy) | 169 ± 40 | 165 ± 47 | 4 [−5; 13] | 0.87 (P = 3.10−8) |
D20 (Gy) | 250 ± 67 | 251 ± 78 | − 1 [− 15; 14] | 0.89 (P = 7.10−9) |
D50 (Gy) | 156 ± 44 | 144 ± 51 | 12 [0; 25] | 0.79 (P = 4.10−6) |
D70 (Gy) | 104 ± 36 | 91 ± 38 | 13 [1; 25]* | 0.67 (P = 3.10−4) |
V205 (%) | 30 ± 18 | 30 ± 16 | 0 [− 3; 4] | 0.85 (P = 1.10−7) |
DNL (Gy) | 36 ± 16 | 34 ± 15 | 1 [− 1; 4] | 0.91 (P = 6.10−10) |
MS microsphere, MAA macroaggregated albumin, SD standard deviation, DT mean dose to the tumor, D20 minimum dose to 20% of the tumor volume, D50 minimum dose to 50% of the tumor volume, D70 minimum dose to 70% of the tumor volume, V205 percentage of the volume receiving more than 205 Gy, DNL mean dose to the normal liver. Bias and correlation are with respect to 90Y-MS PET
*P ≤ 0.05