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. 2019 Jul 16;13:320. doi: 10.3389/fncel.2019.00320

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Copyright © 2019 Smith, Germundson, Combs, Vendsel and Nagamoto-Combs.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Physical growth and adaptive immunity development during BLG sensitization. (A) Weights of mice were recorded during Weeks 1, 6, and 7 of sensitization to assess potential impact of the sensitization regime on overall health and growth. (B,C) Serum isolated from the terminal blood was used to quantify the levels of BLG-specific IgE (B) or IgG1 (C) using ELISA. Values shown in the graphs indicate the group average ± SEM, *p < 0.05; ***p < 0.001. (Mann-Whitney test), male sham: n = 8; male BLG: n = 8; female sham: n = 8; female BLG: n = 8.