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. 2019 Jul 16;13:718. doi: 10.3389/fnins.2019.00718

FIGURE 2.

FIGURE 2

Assessment of sensorimotor deficit between D-1 and D14 and of spontaneous locomotor activity measured at D28 in ND-PBS, untreated non-diabetic mice; ND-hADMSC, treated non-diabetic mice; D-PBS, untreated diabetic mice and D-hADMSC, treated diabetic mice (n = 13–20) (A) and NHT-PBS, untreated non-hypertensive mice; NHT-hADMSC, treated non-hypertensive mice; HT-PBS, untreated hypertensive mice and HT-hADMSC, treated hypertensive mice (n = 8–20) (B). Diabetic and hypertensive mice showed a more severe sensorimotor deficit than control mice during the whole evaluation until they fully recovered at D14 except D-PBS mice (p < 0.01 versus ND-PBS and p < 0.01 versus ND-hADMSC). No differences were evidenced between untreated and treated mice. At D28, no differences were evidenced between mice in the total distance traveled or mean velocity at open field; ∗p < 0.05, ∗∗p < 0.01, ∗∗∗∗p < 0.0001 between ND-PBS versus D-PBS mice and NHT-PBS versus HT-PBS mice; #p < 0.05, ##p < 0.01, ###p < 0.001, ####p < 0.0001 between ND-PBS versus D-hADMSC and between NHT-PBS versus HT-hADMSC; §p < 0.05, §§p < 0.01, §§§p < 0.001, §§§§p < 0.0001 between ND-hADMSC versus D-PBS and between NHT-hADMSC versus HT-PBS; $p < 0.05, $$p < 0.01, $$$$p < 0.0001 between ND-hADMSC versus D-hADMSC and NHT-hADMSC versus HT-hADMSC.