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. 2019 Jul 16;13:718. doi: 10.3389/fnins.2019.00718

FIGURE 8.

FIGURE 8

Assessment of GFAP+ cells density at D9 and D40 in ND-PBS, untreated non-diabetic mice; ND-hADMSC, treated non-diabetic mice; D-PBS, untreated diabetic mice and D-hADMSC, treated diabetic mice (D9: n = 5–10, D40: n = 5–11) (A) and NHT-PBS, untreated non-hypertensive mice; NHT-hADMSC, treated non-hypertensive mice; HT-PBS, untreated hypertensive mice and HT-hADMSC, treated hypertensive mice (D9: n = 7–9, D40: n = 6–11) (B). hADMSC did not significantly modify the astrocytes density whatever the risk factor. Between D9 and D40, there was a significant reduction in activated astrocytes in ND-PBS, ND-hADMSC, D-PBS, and D-hADMSC mice and a significant increase in activated astrocytes in HT-PBS and HT-hADMSC mice; ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, ∗∗∗∗p < 0.0001. GFAP immunostaining, scale bar: 50 μm; C, cortex; V, ventricle; SVZ, subventricular zone; green squares: regions of interest (C).