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Monitoring of disease course, immunoglobulin and B-cell subset levels in INS patients who developed a severe de-novo hypogammaglobulinemia following anti-CD20 treatment. RTX, rituximab; OFA, ofatumumab; SCIg, subcutaneous immunoglobulin infusion; IVIg, intravenous immunoglobulin infusion; PDN, prednisone; MMF, mycophenolate mofetil; CNIs, calcinuerin inhibitors, IFN, interferon.
