Table 2.
Univariate and multivariate Cox analysis of CSS.
| Characteristics | 5-year CSS % | 10-year CSS % | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|---|---|
| HR [95%CI] | P | HR [95%CI] | P | ||||
| Gleason score | 3+4 = 7 | 98.70 | 96.30 | 1 | <0.001 | 1 | <0.001 |
| 4+3 = 7 | 96.60 | 91.40 | 2.538 [2.351–2.740] | 1.617 [1.495–1.749] | |||
| Age at diagnosis | ≤60 | 99.00 | 97.00 | 1 | <0.001 | 1 | |
| 60–70 | 98.70 | 96.10 | 1.318 [1.182–1.470] | 1.153 [1.033–1.288] | 0.012 | ||
| >70 | 96.00 | 90.10 | 3.602 [3.254–3.987] | 1.823 [1.633–2.037] | <0.001 | ||
| Race | Black | 97.50 | 94.10 | 1 | <0.001 | 1 | |
| White | 98.20 | 95 | 0.812 [0.735–0.897] | 1.085 [0.978–1.203] | 0.123 | ||
| Others | 98.50 | 96.80 | 0.555 [0.446–0.691] | 0.630 [0.505–0.786] | <0.001 | ||
| Marital status | Married | 98.50 | 95.70 | 1 | <0.001 | 1 | <0.001 |
| Others | 96.80 | 92.30 | 1.836 [1.692–1.991] | 1.313 [1.207–1.428] | |||
| AJCC stage | II | 98.70 | 96.00 | 1 | <0.001 | 1 | <0.001 |
| III/IV | 94.90 | 90.00 | 2.806 [2.589–3.043] | 1.763 [1.429–2.175] | |||
| Stage T | T1/T2 | 98.20 | 95.20 | 1 | <0.001 | 1 | 0.004 |
| T3/T4 | 97.70 | 93.60 | 1.337 [1.211–1.476] | 1.316 [1.090–1.590] | |||
| Stage N | N0 | 98.30 | 95.30 | 1 | <0.001 | 1 | <0.001 |
| N1 | 84.00 | 74.00 | 6.929 [6.045–7.941] | 1.649 [1.411–1.928] | |||
| Stage M | M0 | 98.70 | 95.70 | 1 | <0.001 | 1 | <0.001 |
| M1 | 49.80 | 34.50 | 35.753 [32.28–39.60] | 4.176 [3.432–5.082] | |||
| PSA (ng/ml) | ≤10 | 99.20 | 97.00 | 1 | <0.001 | 1 | <0.001 |
| 10–20 | 97.40 | 93.40 | 2.512 [2.268–2.781] | 1.588 [1.431–1.762] | |||
| >20 | 89.00 | 79 | 9.100 [8.347–9.922] | 2.936 [2.649–3.253] | |||
| Treatment | No surgery and radiation | 90.90 | 81.80 | 1 | <0.001 | 1 | <0.001 |
| Only radiation without surgery | 98.00 | 93.80 | 0.274 [0.252–0.298] | 0.490 [0.446–0.537] | |||
| Only surgery without radiation | 99.70 | 98.50 | 0.062 [0.055–0.070] | 0.133 [0.115–0.154] | |||
| Both radiation and surgery | 98.80 | 94.30 | 0.267 [0.214–0.332] | 0.308 [0.241–0.394] | |||