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. 2019 Jul 16;9:646. doi: 10.3389/fonc.2019.00646

Table 2.

Univariate and multivariate Cox analysis of CSS.

Characteristics 5-year CSS % 10-year CSS % Univariate analysis Multivariate analysis
HR [95%CI] P HR [95%CI] P
Gleason score 3+4 = 7 98.70 96.30 1 <0.001 1 <0.001
4+3 = 7 96.60 91.40 2.538 [2.351–2.740] 1.617 [1.495–1.749]
Age at diagnosis ≤60 99.00 97.00 1 <0.001 1
60–70 98.70 96.10 1.318 [1.182–1.470] 1.153 [1.033–1.288] 0.012
>70 96.00 90.10 3.602 [3.254–3.987] 1.823 [1.633–2.037] <0.001
Race Black 97.50 94.10 1 <0.001 1
White 98.20 95 0.812 [0.735–0.897] 1.085 [0.978–1.203] 0.123
Others 98.50 96.80 0.555 [0.446–0.691] 0.630 [0.505–0.786] <0.001
Marital status Married 98.50 95.70 1 <0.001 1 <0.001
Others 96.80 92.30 1.836 [1.692–1.991] 1.313 [1.207–1.428]
AJCC stage II 98.70 96.00 1 <0.001 1 <0.001
III/IV 94.90 90.00 2.806 [2.589–3.043] 1.763 [1.429–2.175]
Stage T T1/T2 98.20 95.20 1 <0.001 1 0.004
T3/T4 97.70 93.60 1.337 [1.211–1.476] 1.316 [1.090–1.590]
Stage N N0 98.30 95.30 1 <0.001 1 <0.001
N1 84.00 74.00 6.929 [6.045–7.941] 1.649 [1.411–1.928]
Stage M M0 98.70 95.70 1 <0.001 1 <0.001
M1 49.80 34.50 35.753 [32.28–39.60] 4.176 [3.432–5.082]
PSA (ng/ml) ≤10 99.20 97.00 1 <0.001 1 <0.001
10–20 97.40 93.40 2.512 [2.268–2.781] 1.588 [1.431–1.762]
>20 89.00 79 9.100 [8.347–9.922] 2.936 [2.649–3.253]
Treatment No surgery and radiation 90.90 81.80 1 <0.001 1 <0.001
Only radiation without surgery 98.00 93.80 0.274 [0.252–0.298] 0.490 [0.446–0.537]
Only surgery without radiation 99.70 98.50 0.062 [0.055–0.070] 0.133 [0.115–0.154]
Both radiation and surgery 98.80 94.30 0.267 [0.214–0.332] 0.308 [0.241–0.394]