Table 4.
Distribution of phylogenetic groups and virulence factors among the 232 UPEC isolates in HA and CA infections
| Variable | Prevalence of trait, n (%) of isolates | p-value | ||
|---|---|---|---|---|
| Total | HA | CA | ||
| N=232 | N=139 | N=93 | ||
| Phylogenetic group | ||||
| B2 | 42 (18.1) | 23 (16.5) | 19 (20.4) | 0.489 |
| B1 | 18 (7.8) | 9 (6.4) | 9 (9.7) | 0.454 |
| A | 37 (15.9) | 19 (13.7) | 18 (19.3) | 0.275 |
| D | 135 (58.2) | 90 (64.7) | 45 (48.4) | 0.015e |
| Virulence factor | ||||
| Protectin | ||||
| kpsM | 36 (15.5) | 21 (15.1) | 15 (16.1) | 0.855 |
| neuA | 116 (50) | 67 (48.2) | 49 (52.7) | 0.592 |
| Cytotoxin | ||||
| hlyA | 10 (4.3) | 4 (2.8) | 6 (6.4) | 0.205 |
| cnf | 53 (22.8) | 38 (27.3) | 15 (16.1) | 0.056 |
| sat | 31 (13.4) | 19 (13.7) | 12 (12.9) | 1.00 |
| Adhesin | ||||
| FimH | 222 (95.7) | 133 (95.7) | 89 (95.7) | 1.00 |
| Pap (papG I, II, and III, papC) | 104 (44.8) | 62 (44.6) | 42 (45.2) | 1.00 |
| sfaA | 15(6.4) | 3 (2.1) | 12 (12.9) | 0.002f |
| draD | 23(9.9) | 8 (5.7) | 15 (16.1) | 0.013f |
| Microcin gene | ||||
| mcmA | 17 (7.3) | 14 (10) | 3 (3.2) | 0.070 |
| mchB | 20 (8.6) | 14 (10) | 6 (6.4) | 0.475 |
| mciA | 9 (3.9) | 8 (5.7) | 1 (1) | 0.089 |
| mceA | 26 (11.2) | 19 (13.6) | 7 (7.5) | 0.202 |
| cvaC | 11 (4.7) | 9 (6.4) | 2 (2.1) | 0.207 |
Notes: ePhylogroup D more statistically detected in the HA population, compared to the CA population (p<0.05). fAdhesin factors sfaAand draDmore statistically detected in the CA population, compared to the HA population (p<0.05).
Abbreviations: CA, community acquired; HA, hospital acquired; UPEC, uropathogenic Escherichia coli.