Table 5.
Distribution of virulence genes/phylogenetic groups among the UPEC strain in the UTI patients
| Variable | Phylogenetic group | p-value | ||||
|---|---|---|---|---|---|---|
| B2, n (%) | B1, n (%) | D, n (%) | A, n (%) | |||
| Capsule | kpsMb,c | 5 (11.9) | – | 31 (23) | – | ˂0.001 |
| neuAb | 7 (16.7) | 3 (16.7) | 103 (76.3) | 3 (8.1) | ˂0.001 | |
| Cytotoxin | hlyAc | 3 (7.1) | – | 7 (5.2) | – | 0.4 |
| cnfb | 7 (16.7) | 3 (16.7) | 40 (29.6) | 3 (8.1) | 0.022 | |
| sat | 7 (16.7) | 3 (16.7) | 19 (14.1) | 2 (5.4) | 0.41 | |
| Adhesin/fimbria | FimH | 40 (95.2) | 17 (94.4) | 132 (97.8) | 33 (89.2) | 0.09 |
| Pap (papGI, II, I and II, C)b | 15 (35.7) | 3 (16.7) | 74 (54.8) | 12 (36.4) | 0.003 | |
| sfaAc | 6 (14.3) | – | 9 (6.7) | – | 0.047 | |
| draD | 6 (14.3) | – | 12 (8.9) | 5 (13.5) | 0.307 | |
| Microcin gene | mcmA | 7 (16.7) | – | 7 (5.2) | 3 (8.1) | 0.067 |
| mchB | 5 (11.9) | 3 (16.7) | 9 (6.7) | 3 (8.1) | 0.342 | |
| mciA | 2 (4.8) | – | 5 (3.7) | 2 (5.4) | 0.809 | |
| mceA | 8 (19) | 3 (16.7) | 11 (8.1) | 4 (10.8) | 0.185 | |
| cvaC | 3 (7.1) | – | 7 (5.2) | 1 (2.7) | 0.757 | |
Notes: bVirulence genes more statistically detected in phylogroup D, in comparison with phylogroups B2, A, and B1 (p<0.05). cVirulence genes exclusively detected in phylogroups B2 and D.
Abbreviation: UTI, urinary tract infection; UPEC, uropathogenic Escherichiacoli.