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. 2019 Jul 18;12:5835–5848. doi: 10.2147/OTT.S207211

Table 1.

Correlation of PKC-iota and GLUT1 expression in 81 primary NSCLC tumor tissues with different clinicopathological parameters

Variable Number PKC-iota expression GLUT1 expression
Low expression High expression P-value Low expression High expression P-value
Age (years)
 ≤60 24 9 15 0.402 12 12 0.084
 >60 57 16 41 17 40
Gender
 Female 23 9 14 0.310 9 14 0.694
 Male 58 16 42 20 38
Smoke
 Yes 57 16 41 0.402 23 34 0.188
 No 24 9 15 6 18
Pathological type
 SQCC 31 5 26 0.024* 6 25 0.015*
 ADC 50 20 30 23 27
Lesion length (cm)
 ≤3 22 12 10 0.005* 14 8 0.001**
 >3 59 13 46 15 44
Nodal metastasis
 No 53 21 32 0.019* 24 29 0.014*
 Yes 28 4 24 5 23
TNM stage
 Stage I 38 18 20 0.003** 19 19 0.012*
 Stage II-IV 43 7 36 10 33

Notes: *P<0.05, **P<0.005.

Abbreviations: PKC-iota, protein kinase C-iota; GLUT1, glucose transporter 1; NSCLC, nonsmall cell lung cancer; SQCC, squamous carcinoma; ADC, adenocarcinoma.