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. 2019 Jul 23;8(7):995–1011. doi: 10.1002/open.201900227

Table 1.

K D and MIC values against M. tuberculosis H37Rv.

Compound K D (μM) Soret peak shift (nm) MIC (μg/mL)
10 a 60.5±10.5 416.5 to 419 12.5
10 b 53.6±6.8 416.5 to 421 12.5
10 c 18.3±3.4 416.5 to 420 1.562
10 d 53.7±5.9 416.5 to 420 0.781
10 e 22.5±3.5 416.5 to 423 1.562
10 f 0.22±0.01 416.5 to 423.5 1.562
10 g 4.81±0.31 416.5 to 419.5 1.562
10 h 2.91±0.14 416.5 to 423.5 3.125
10 i 10.1±0.3 416.5 to 422.5 3.125
10 j 3.31±0.05 416.5 to 423.5 25
11 a 115.3±27.0 416.5 to 417.5 >100
11 b 249.7±51.6 416.5 to 417.5 >100
13 a 83.2±3.9 416.5 to 423.5 100
13 b 85.6±12.4 416.5 to 417.5 >100
14 a 218.6±13.6 416.5 to 419.5 >100
14b 39.0±8.2 416.5 to 417.5 >100
23 34.5±4.8 416.5 to 418 >100
24 105±7 416.5 to 418 >100
25 22.9±0.2 416.5 to 418.5 25
26 98.3±7.4 416.5 to 416 100
1 2.6±0.2 416.5 to 424 12.5
2 73.5±0.7 416.5 to 422.5 50
Fluconazole 8.6±0.2 >100
Clotrimazole 0.07±0.01 20
cYY 5.82±0.16