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. 2019 Jun 25;14(7):1660–1671. doi: 10.1021/acschembio.9b00458

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Copyright © 2019 American Chemical Society

This is an open access article published under an ACS AuthorChoice License, which permits copying and redistribution of the article or any adaptations for non-commercial purposes.

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¹⁹F CPMG experiments for the fluorinated monosaccharide small library. (a) The employed concentrations were 40 μM CRD DC-SIGN and 0.8 mM of each monosaccharide. [(Bottom) The first spectrum was acquired with 8 ms total echo time; (middle) the spectrum was acquired with 2000 ms echo time; (top) the spectrum with 2000 ms echo time after the addition of 20 mM EDTA-d12. The red asterisks highlight those ¹⁹F signals whose T2 values show a faster decay.] (b) Representation of the ¹⁹F T2 decay curves obtained for every species in the mixture, in the absence (dark color) and the presence of DC-SIGN (light color).

¹⁹F CPMG experiments for the fluorinated monosaccharide small library. (a) The employed concentrations were 40 μM CRD DC-SIGN and 0.8 mM of each monosaccharide. [(Bottom) The first spectrum was acquired with 8 ms total echo time; (middle) the spectrum was acquired with 2000 ms echo time; (top) the spectrum with 2000 ms echo time after the addition of 20 mM EDTA-d12. The red asterisks highlight those ¹⁹F signals whose T2 values show a faster decay.] (b) Representation of the ¹⁹F T2 decay curves obtained for every species in the mixture, in the absence (dark color) and the presence of DC-SIGN (light color).