Table 2.
Outcome measure | No personality disorder | Comorbid personality disorder | Total | Comorbid personality disorder (yes/no) | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Mean (s.d.) | N | Effect size d (95% CI) |
Mean (s.d.) |
N | Effect size d (95% CI) |
Mean (s.d.) | N | Effect size d (95% CI) |
Estimated mean difference (s.e.) | |
HRSD | ||||||||||
Baseline | 21.73 (4.36) | 63 | 23.20 (5.28) | 133 | 22.72 (5.04) | 196 | −1.19 (1.08) | |||
Week 10 | 15.58 (8.33) | 52 | 18.25 (8.24) | 117 | 17.43 (8.33) | 169 | −2.89 (1.15)* | |||
Week 22 | 13.20 (7.79) | 59 | 1.70 (1.28–2.12) | 15.69 (8.97) | 113 | 1.31 (1.02–1.60) | 14.84 (8.64) | 172 | 1.44 (1.20–1.67) | −2.37 (1.12)* |
Week 52 | 10.38 (6.48) | 47 | 2.40 (1.87–2.93) | 14.62 (9.67) | 98 | 1.46 (1.14–1.77) | 13.25 (8.96) | 145 | 1.70 (1.43–1.97) | −4.47 (1.21)* |
IDS | ||||||||||
Baseline | 37.83 (8.78) | 61 | 43.60 (9.88) | 117 | 41.62 (9.88) | 178 | −1.59 (1.65) | |||
Week 10 | 27.83 (13.25) | 49 | 35.53 (14.77) | 102 | 33.03 (14.70) | 151 | −4.66 (1.83)* | |||
Week 22 | 22.24 (13.10) | 50 | 1.78 (1.31–2.24) | 32.16 (16.41) | 91 | 1.31 (0.98–1.64) | 28.64 (16.00) | 141 | 1.48 (1.21–1.75) | −4.99 (1.85)* |
Week 52 | 16.45 (12.01) | 39 | 3.11 (2.44–3.78) | 26.89 (16.55) | 64 | 1.53 (1.12–1.94) | 22.93 (15.78) | 103 | 1.94 (1.60–2.28) | −5.58 (2.10)* |
OQ interpersonal relations | ||||||||||
Baseline | 16.41 (6.18) | 39 | 21.92 (5.16) | 95 | 20.31 (6.00) | 134 | −1.68 (0.98) | |||
Week 10 | 13.39 (6.29) | 45 | 19.66 (7.12) | 95 | 17.64 (7.45) | 140 | −3.96 (1.11)* | |||
Week 22 | 11.97 (6.04) | 35 | 0.98 (0.40–1.55) | 18.57 (6.90) | 63 | 0.69 (0.29–1.08) | 16.21 (7.30) | 98 | 0.78 (0.46–1.11) | −4.11 (1.19)* |
Week 52 | 11.13 (6.63) | 23 | 0.74 (0.07–1.42) | 16.61 (7.70) | 36 | 1.37 (0.81–1.93) | 14.47 (7.73) | 59 | 1.06 (0.63–1.48) | −0.91 (1.47) |
OQ social role functioning | ||||||||||
Baseline | 14.17 (5.24) | 48 | 16.95 (5.22) | 96 | 16.02 (5.37) | 144 | −1.29 (0.78) | |||
Week 10 | 11.54 (4.33) | 45 | 14.53 (5.48) | 97 | 13.58 (5.32) | 142 | −2.48 (0.91)* | |||
Week 22 | 11.14 (5.08) | 42 | 0.92 (0.42–1.42) | 13.39 (5.78) | 66 | 0.85 (0.46–1.24) | 12.52 (5.60) | 108 | 0.88 (0.58–1.19) | −1.46 (0.95) |
Week 52 | 10.25 (5.53) | 24 | 0.71 (0.05–1.36) | 12.62 (5.88) | 39 | 0.76 (0.28–1.25) | 11.71 (5.82) | 63 | 0.74 (0.35–1.13) | −1.62 (1.24) |
EQ-5D | ||||||||||
Baseline | 0.44 (0.30) | 56 | 0.37 (0.31) | 117 | 0.39 (0.31) | 173 | 0.04 (0.04) | |||
Week 10 | 0.62 (0.28) | 49 | 0.48 (0.32) | 102 | 0.52 (0.31) | 151 | 0.15 (0.05)* | |||
Week 22 | 0.71 (0.30) | 45 | 1.17 (0.71–1.64) | 0.56 (0.34) | 75 | 1.00 (0.65–1.34) | 0.62 (0.33) | 120 | 1.06 (0.79–1.34) | 0.09 (0.05) |
Week 52 | 0.73 (0.30) | 28 | 1.57 (0.93–2.22) | 0.64 (0.33) | 42 | 0.97 (0.51–1.43) | 0.67 (0.32) | 70 | 1.15 (0.78–1.52) | 0.08 (0.06) |
EQ-5D, EuroQol-5D; HRSD, Hamilton Rating Scale for Depression; IDS, Inventory of Depressive Symptomatology; OQ, Outcome Questionnaire; s.d., standard deviation; s.e., standard error; CI, confidence interval.
P < 0.05.