Figure 1. Data Sets for Deep Learning Model Development and Testing.

The Prostate, Lung, Colorectal, and Ovarian (PLCO) trial development data set includes all baseline and year 1 chest radiographs, with several participants having more than 1 chest radiograph from either time point. The PLCO and National Lung Screening Trial (NLST) testing data sets include a single baseline chest radiograph per person. ACRIN indicates American College of Radiology Imaging Network; CT, computed tomography.