Skip to main content
. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Int J Hyperthermia. 2018 Apr 24;34(7):934–942. doi: 10.1080/02656736.2018.1462535

Figure 1. RFA thermal dose settings during hepatic ablation stimulate variable distant subcutaneous tumor growth.

Figure 1.

Animals implanted with subcutaneous R3230 tumors were treated with low- (60°Cx10min), medium- (70°Cx5min) and high-dose (90°Cx2min) hepatic RF ablation compared to sham treatment. After hepatic ablation (Day 0), the growth rates of the distant tumors significantly increased for low- and medium-dose RFA compared to high-dose RFA and sham treatment. This resulted in significantly larger tumor size (p<0.05) at day 7 for low- and medium-dose RFA compared high-dose RFA and sham treatment. A significant increase in tumor growth was still seen in high-dose RFA compared to sham (p<0.05), however the effect is much less pronounced.