Table 4.

Comparison of main diagnostic categories among FUO case-series in 2005–2015 and FUO case-series in 1995–2004

	Old case-series (1995–2004)	New case-series (2006–2014)	p-value
N° of patients	1488	3164	–
Male (%)	56,2	49,6	–
Mean age	40,6	45,8	–
Infectious Diseases	545 (37%)	1197 (38%)	0,428
Neoplasm	167 (11%)	366 (12%)	0,731
NIID	236 (16%)	661 (21%)	< 0,001
Others	155 (10%)	206 (7%)	< 0,001
No diagnosis	385 (26%)	734 (23%)	0,051

Variables with significant statistical association (p < 0,05) are in bold