Table 2.
Differences between study variables from 6 months prior to enrollment, baseline and month 6
| Factor | 6 Months prior to enrollment | Baseline | Month 6 | 95% CI for changes | 6 Months prior to enrollment to baseline | Baseline to month 6 |
|---|---|---|---|---|---|---|
| [Mean ± SD] | [Mean ± SD] | [Mean ± SD] | P value | P value | ||
| ETDRS BCVA | 70.1 ± 7.7 | 70.0 ± 7.2 | 71.5 ± 8.9 | 1.55 (− 2.08, 5.18) | 0.95 | 0.38 |
| Central subfield thickness (µm) | 420.8 ± 100.5 | 419.7 ± 92.0 | 303.8 ± 73.1 | − 116.0 (− 150.8, − 81.15) | 0.99 | < 0.001 |
| Cube volume (mm3) | N/A | 11.5 ± 1.4 | 10.7 ± 1.2 | − 0.86 (− 1.06, − 0.65) | N/A | < 0.001 |
| Cube average thickness (µm) | N/A | 320.7 ± 38.6 | 297.2 ± 33.1 | − 23.50 (− 29.36, − 17.64) | N/A | < 0.001 |
| Foveal avascular zone (mm2) | N/A | 0.31 ± 0.13 | 0.33 ± 0.11a | − 0.03(− 0.11, 0.05) | N/A | 0.47 |
Statistically significant values are in bold italic
ETDRS early treatment diabetic retinopaty study, BCVA best corrected visual acuity, CI confidence interval
an = 18