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. 2019 Jul 22;14:29. doi: 10.1186/s13024-019-0329-1

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Change in Circular Dichroism (CD) signal in the far UV caused by the binding of αS to an excess of DMPS vesicles. This demonstrates a shift from a random coil structure in the absence of lipid vesicles (green), towards an alpha-helical secondary structure in the presence of DMPS lipid vesicles (red). Meade et. al. unpublished data reproducing data from Galvagnion et al. [34]