Table 2.

ESCC Patients’ clinicopathological characteristics according to NLR and SIS

characteristics	NLR			SIS groups
	NLR ≤ 2.27	NLR > 2.27	P	SIS = 0	SIS = 1	SIS = 2	P
	N = 228	N = 129		N = 119	N = 148	N = 90
Gender			0.003				< 0.001
Male	167	112		71	128	80
Female	61	17		48	20	10
Age			0.874				0.087
≤ 65 years old	177	99		95	119	62
>65 years old	51	30		24	29	28
Vascular Invasiona			0.453				0.944
No	197	115		103	130	79
Yes	31	14		16	18	11
Tumor cell differentiationa			0.561				0.412
G1	31	23		14	21	15
G2	168	90		90	109	18
G3	29	16		15	18	12
Tumor locationa			0.728				0.324
Upper	41	16		21	26	7
Middle	164	96		91	105	17
Lower	23	14		7	64	13
Tumor length			< 0.001				0.004
≤ 5 cm	167	69		91	98	49
> 5 cm	61	60		28	50	41
T stage			0.002				0.102
T1	33	7		18	14	8
T2	53	18		26	34	11
T3	124	85		60	89	60
T4	18	19		15	11	11
N stage			0.266				0.161
N0	104	51		58	65	32
N1–3	124	78		61	83	58
Stage			0.109				0.117
I	24	5		14	12	3
II	81	24		43	51	29
III	90	59		49	61	39
IVa	33	23		13	24	19

^a While N ≥ 40 and 1 ≤ theoretical frequency(T)<5, the Fisher exact test was used to compare the influencing factors