Table 1.
Patient clinical characteristics
| n | Median (IQR) | p value* | |
|---|---|---|---|
| Anthropometric | |||
| Sex (F, M) | 93 | 71, 22 | – |
| Age (year) | 93 | 17 (3) | 0.04 |
| Height (cm) | 93 | 164 (13) | 0.3 |
| Weight (kg) | 93 | 126 (45) | 0.36 |
| BMI (kg/m2) | 93 | 45.2 (13.2) | 0.38 |
| HDL function | |||
| Cholesterol efflux capacity | 69 | 0.85 (0.17) | – |
| Lipid panel | |||
| Total cholesterol | 69 | 127 (34) | 0.89 |
| LDL-C, mg/dL | 69 | 77 (38) | 0.86 |
| HDL-C, mg/dL | 69 | 40 (13) | 0.11 |
| Triglycerides | 69 | 56 (36) | 0.48 |
| NMR spectroscopy | |||
| LDL particle concentration, nmol/L | 69 | 933 (453) | 0.15 |
| HDL particle concentration, µmol/L | 69 | 25.6 (5.3) | 0.46 |
| VLDL particle concentration, nmol/L | 69 | 28.4 (20.4) | 0.09 |
| LDL particle size, nm | 69 | 20.5 (9) | < 0.01 |
| HDL particle size, nm | 69 | 9.2 (0.7) | 0.01 |
| VLDL particle size, nm | 69 | 48.4 (8.35) | 0.17 |
| Metabolic assessment | |||
| Lipoprotein insulin resistance score | 69 | 46 (25) | 0.45 |
| Inflammation assessment | |||
| GlycA | 69 | 429 (90) | 0.15 |
Data are presented as Median (IQR). p value for Pearson product moment correlation coefficient for cholesterol efflux capacity