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. 2019 Jul 22;12:446. doi: 10.1186/s13104-019-4490-y

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — H&E staining of the ovarian tissue. In addition to hyperemia in the ovarian tissue of the VCD treated group, the presence of collagen fibers represents fibrosis of the tissue. Depending on the effect of VCD on follicles, degeneration of primary and secondary follicles is evident