Table 1.
Characteristics of the subjects who provided brain tissue
| Controls | All MDD | p value* | |
|---|---|---|---|
| (n = 12) | (n = 24) | ||
| Age (mean years ± SD) | 46.8 ± 12.1 | 42.2 ± 10.9 | 0.20 |
| Sex (M/F) | 8/4 | 13/11 | 0.72 |
| Caucasian Race | 11 | 23 | 1 |
| Suicide | – | 17 | – |
| Age of onset (mean years ± SD) | – | 29.9 ± 11.9 | – |
| Disease duration (mean years ± SD) | – | 12.3 ± 7.6 | – |
| Alcohol use (%) | 58.3 | 66.6 | 0.72 |
| Drug use (%) | 33 | 33 | 1 |
| Brain pH (mean ± SD) | 6.64 ± 0.18 | 6.65 ± 0.15 | 0.82 |
| PMI (mean hours ± SD) | 25.3 ± 10.6 | 29.7 ± 12.4 | 0.30 |
PMI postmortem interval
*Unpaired t tests and Fisher exact tests were conducted to assess group differences for continuous and discrete variables, respectively