Table 1.
Serum concentrations (mean values ± SEM) of neopterin, nitrite and neurotransmitter precursor amino acids in 19 patients with late-life depression before and after rTMS treatment
| Before rTMS | After rTMS | U | p | |
|---|---|---|---|---|
| Tryptophan (µmol/L) | 58.6 ± 3.56 | 52.5 ± 2.53 | 0.092 | n.s |
| Kynurenine (µmol/L) | 1.85 ± 0.10 | 1.92 ± 0.13 | 0.275 | n.s |
| Kyn/Trp (µmol/mmol) | 33.3 ± 2.53 | 37.2 ± 2.61 | 0.046 | n.s |
| Tyrosine (µmol/L) | 83.9 ± 5.82 | 73.6 ± 5.70 | 0.459 | n.s |
| Phenylalanine (µmol/L) | 98.2 ± 7.22 | 81.4 ± 4.61 | 2.340 | < 0.02 |
| Phe/Tyr (µmol/µmol) | 1.19 ± 0.051 | 1.15 ± 0.061 | 1.516 | n.s |
| Nitrite (µmol/L) | 45.8 ± 7.65 | 40.3 ± 11.4 | 0.872 | n.s |
| Neopterin (nmol/L) | 10.6 ± 3.43 | 11.7 ± 1.24 | 1.423 | n.s |
Kyn/Trp kynurenine to tryptophan ratio, Phe/Tyr phenylalanine to tyrosine ratio