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. 2018 Nov 6;56(7):4820–4837. doi: 10.1007/s12035-018-1401-5

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Prenatal BP-3 exposure decreased expression of autophagy-related genes and autophagosomes formation in embryonic neuronal cells. Analysis with microarray demonstrated 38 genes that were significantly differentially expressed in the BP-3-treated group in comparison to the control groups. Among them, 22 genes were downregulated (green color) and 16 genes were upregulated (red color) in the BP-3-treated samples. Each value represents the mean of two independent experiments (a). Prenatal BP-3 decreased the formation of autophagosomes in mouse embryonic neuronal cells. The data are expressed as the mean ± SE of three independent experiments, consisting of eight replicates per group. ***p < 0.001 versus control cultures (b)