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Reduced HDAC and sirtuin activities as well as decreased sumoylation in mouse neurons prenatally treated with BP-3. The influence of prenatal BP-3 on HAT (a), HDAC (b), and sirtuin (c) activities as well as global protein sumoylation (d) in cortical cultures at 7 DIV. Each bar represents the mean of three independent experiments ± SE. The number of replicates in each experiment ranged from 2 to 3. **p < 0.01 and ***p < 0.001 versus control cultures
