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. 2019 Jan 14;19(4):344–356. doi: 10.1007/s12012-018-9500-0

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 4 — Effects of Sunitinib, L-carnitine and their combination on histopathological changes in cardiac tissues stained with Masson Trichrome (MT) connective tissue stain. a Heart from control rat showing normal myocardial fibers (× 400). b Heart of rat treated with SUN alone showing marked fibrosis (blue colored fibers) with extension to interstitial tissue between myofibers (B1, × 600) and interstitial fibrosis characterized by the presence of many “blue colored” connective tissue fibers, arrowhead, (B2, × 600). c Heart of rat treated with l-carnitine alone showing normal myocardial fibers with only thin blue-colored collagen fibers, arrowhead, (× 400). d Heart of rat treated with SUN plus l-carnitine showing marked reduction in the amount of connective tissue fibers (× 400)