Table 2.

Univariate analysis examining age, pathologic T-stage, Nottingham grade, intra-tumoral macrophage infiltration, and CD163-expression by tumor cells among the intrinsic subtypes of breast cancer

Intrinsic subtypes
	Luminal A N (%)	Luminal B HER2pos N (%)	Luminal B HER2neg N (%)	Triple negative N (%)	P
Age groups (years)
≤ 40	5 (12)	1 (20)	4 (29)	2 (18.2)
41–50	8 (18)	2 (40)	3 (21)	3 (27.3)
51–60	11 (26)	1 (20)	2 (14.3)	1 (9.1)
61–70	9 (21)	1 (20)	2 (14.3)	1 (9.1)
≥ 70	10 (23)	0 (0)	3 (21.4)	4 (36.3)	0.83
Pathologic T-stage
pT1	38 (88)	5 (100)	11 (79)	6 (54.5)
pT2	5 (12)	0 (0)	3 (21)	5 (45.5)	0.04
Nottingham grading system
NHG 1	14 (33)	0 (0)	1 (7)	0 (0)
NHG 2	23 (53)	3 (60)	6 (43)	3 (27)
NHG 3	6 (14)	2 (40)	7 (50)	8 (73)	0.002
CD163-expression
Negative (< 15%)	37 (86)	2 (50)	10 (71)	8 (73)
Positive (≥ 15%)	6 (14)	2 (50)	4 (29)	3 (27)	0.25
Macrophage infiltration
Low	31 (72)	1 (25)	3 (21)	2 (18)
Moderate	10 (23)	3 (75)	3 (43)	5 (46)
High	2 (5)	0 (0)	5 (36)	4 (36)	0.001