Table 4.

Importance of each factor based on screening experiment evaluated for four different outcome criteria: maximum force, fracture energy, crack length and crack score

ANOVA (%TSS)		Maximum force			Fracture energy			Crack length			Crack score
X screen	Factors	Long	Radial	Trans	Long	Radial	Trans	Long	Radial	Trans	Long	Radial	Trans
1	E mat	48.0*	30.2*	8.5*	0.7	0.1	2.8	3.2	0.6	0.1	7.5*	0.1	0.5
2	E ost	2.6*	8.9*	12.9*	3.6	3.5	0.6	4.7	13.4*	7.8	2.7	17.5*	4.2
3	E cl	0.1	1.3	15.8*	7.9	3.7	1.2	15.6	22.0*	14.5*	24.4*	17.5*	8.7
4	v mat	0.7	1.4	2.3	0.9	0.1	0.5	0.9	0.3	0.3	2.7	1.5	0.1
5	v ost	0.0	0.7	0.3	0.0	0.8	0.3	1.1	0.0	0.2	0.3	1.5	0.1
6	v cl	0.4	0.2	1.6	0.1	0.1	0.3	0.0	0.2	1.0	0.3	3.0	0.1
7	${\epsilon }_{\max ,\text{mat}}^0$	39.0*	44.8*	7.0	0.9	0.7	3.4	2.2	0.0	0.0	0.3	1.5	0.1
8	${\epsilon }_{\max ,\text{ost}}^0$	0.9	2.5*	1.9	2.7	0.0	0.4	2.6	0.7	1.6	2.7	3.0	0.5
9	${\epsilon }_{\max ,\text{cl}}^0$	0.0	0.3	5.1	14.9	3.9	0.1	25.1	16.8*	41.9*	24.4*	26.8*	37.4
10	${\epsilon }_{n,\text{cl}}^0$	0.0	0.3	6.4	0.0	0.0	1.4	0.0	0.0	15.7*	0.3	0.5	11.5
11	${\epsilon }_{s,\text{cl}}^0$	0.1	0.5	1.5	4.5	3.5	0.8	10.9	12.6*	5.7	14.8*	13.7*	4.2
12	G mat	4.3*	0.0	2.1	37.5*	46.7*	0.7	0.2	0.3	0.2	0.3	0.1	0.1
13	G ost	0.0	0.2	2.7	0.5	19.6*	9.6*	0.0	2.7	0.3	0.3	4.9	4.2
14	G cl	0.1	0.5	0.0	4.5	3.1	35.2*	0.8	1.1	0.0	2.7	0.1	0.5
Total sum (%)		96.2	91.8	68.1	78.7	85.8	57.3	67.3	70.7	89.3	83.7	91.7	72.2

The results are given for models with longitudinal, radial and transversal osteons. Significant results in the ANOVA analysis (p < 0.05) are indicated with *, and contributions higher than 5% are shown in bold font