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. 2019 May 6;47(8):1815–1826. doi: 10.1007/s10439-019-02280-7

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Boxplots for experimental and control groups with median (red line), quartiles (25% and 75%), and outliers (red crosses) of in vitro measured (white bars), in vitro predicted (grey bars), and in vivo predicted (black bars) for the 4 distal locations at increasing distances from the lesion. Values are presented for cartilage thickness (a), full-thickness proteoglycan content (b), and full-thickness collagen orientation angle (c). For each location, experiment and control groups had 12–14 and 6 measurements, respectively.