Table 1.
Characteristics of the Study Subjects According to Groupsa
| Group 1 (n=35) | Group 2 (n=42) | Group 3 (n=32) | P value | |
|---|---|---|---|---|
| Gestational age, week (mean±SD) | 31.2±4.8 | 31.5±4.8 | 37±2.8 | 1–2: 0.59 |
| 2–3: 0.001 | ||||
| 1–3: 0.001 | ||||
| Birth weight (g) (mean±SD) | 1,710±871 | 1,555±783 | 2,843±843 | 1–2: 0.67 |
| 2–3: 0.001 | ||||
| 1–3: 0.001 | ||||
| Male gender, n(%) | 23 (65.7) | 26 (61.9) | 18 (56.3) | 0.72 |
| Age at sepsis evaluation, day (median, range) | 8 (1–28) | 12 (1–29) | 1 (1–20) | 0.001 |
| Antenatal steroid, n(%) | 12 (34.3) | 16 (38.1) | 4 (12.5) | 0.03 |
| Cesarean delivery, n(%) | 25 (71.4) | 32 (76.2) | 24 (75.0) | 0.88 |
| Premature rupture of membranes >24 hr, n(%) | 7 (20.0) | 9 (21.4) | 5 (15.6) | 0.81 |
| 5 min Apgar score (<7), (median, range) | 5 (14.3) | 7 (16.7) | 2 (6.3) | 0.35 |
| Length of hospital, day (median, range) | 27 (0–87) | 21 (0–91) | 1 (1–27) | 0.001 |
| Mortality, n(%) | 7 (20.0) | 0 (0.0) | 0 (0.0) | 0.001 |
a
aGroup 1: newborns with proven or clinical sepsis. Group 2: newborns with disease without infection. Group 3: healthy newborns.