Table 3.
Characteristics of the Sepsis Evaluation According to Groupsa
| Group 1 (n=35) | Group 2 (n=42) | Group 3 (n=32) | P value | |
|---|---|---|---|---|
| White blood cell count, cells per mm3, (mean±SD) | 11.6±7.0 | 13.0±4.2 | 14.3±4.8 | 0.13 |
| Segmented neutrophils, n(%) | 56.9±19.2 | 51.9±13.8 | 59.2±13.3 | 0.12 |
| Absolute neutrophil count, cells per mm3, (mean±SD) | 7.6±6.0 | 7.1±3.3 | 8.2±4.1 | 0.63 |
| Immature/total neutrophil ratio (>0.2), n (%) | 15 (42.9) | 4 (9.5) | 0 (0.0) | 0.001 |
| Platelet count, cells per mm3, (mean±SD) | 181±95 | 283±125 | 283±85 | P=0.001 |
| 1–2=0.001 | ||||
| 1–3=0.001 | ||||
| 2–3=1.0 | ||||
| IL‐6 (pg/ml) (median, range) | 115 (4.2–1000) | 6.3 (2–141) | 7.9 (2.4–62) | P=0.001 |
| 1–2=0.001 | ||||
| 1–3=0.001 | ||||
| 2–3=0.19 | ||||
| CRP (mg/l) (median, range) | 22.8 (0.5–41.6) | 0.49 (0.09–24) | 0.9 (0.01–32.9) | P=0.001 |
| 1–2=0.001 | ||||
| 1–3=0.001 | ||||
| 2–3=0.16 | ||||
| CD64 (MFI) (median, range) | 207.1 (50.2–524.2) | 58.9 (27.5–165) | 67.6 (29.6–309.8) | 0.001 |
| 1–2=0.001 | ||||
| 1–3=0.001 | ||||
| 2–3=0.12 | ||||
| CD64index | 10.3 (2.5–26.2) | 2.9 (1.3–8.2) | 3.3 (1.4–15.4) | P=0.001 |
a
aGroup 1: newborns with proven or clinical sepsis. Group 2: newborns with disease without infection. Group 3: healthy newborns.