Table 3.
Effect of Oleander Extract on Serum Digoxin Values as Measured by the FPIA, Digoxin II and Digoxin III Assay
| Digoxin, ng/ml, Mean (SD), n=3 | ||||
|---|---|---|---|---|
| Specimen | Vista (Flex Reagent Cartridge) | FPIA | EMIT | Tina Quant |
| Digoxin Pool | 1.1 (0.06) | 1.0 (0.03) | 1.0 (0.16) | 1.0 (0.06) |
| +50 ng/ml Oleandrin | 1.6 (0.00) | 1.5 (0.05) | 1.3 (0.05) | 0.9 (0.06) |
| +100 ng/ml Oleandrin | 1.8 (0.00) | 1.9 (0.06) | 1.5 (0.13) | 1.1 (0.06) |
| +250 ng/ml Oleandrin | 2.0 (0.06) | 1.9 (0.04) | 1.7 (0.04) | 1.2 (0.06) |
| +500 ng/ml Oleandrin | 2.6 (0.00) | 2.7 (0.10) | 2.0 (0.06) | 1.2 (0.00) |
| +1 μg/ml Oleandrin | 3.0 (0.06) | 3.1 (0.07) | 2.5 (0.04) | 1.4 (0.06) |
| +5 μg/ml Oleandrin | 4.4 (0.06) | 4.3 (0.12) | 3.5 (0.07) | 1.5 (0.06) |
| +1 μl/ml Oleander | 1.2 (0.06) | 1.3 (0.03) | 1.2 (0.08) | 0.9 (0.00) |
| +2.5 μl/ml Oleander | 1.7 (0.06) | 1.7 (0.05) | 1.5 (0.06) | 1.1 (0.06) |
| +5 μl/ml Oleander | 2.4 (0.06) | 2.5 (0.07) | 1.9 (0.01) | 1.2 (0.06) |