Table 1.
The Average Within‐Tube Bias of Tumor Markers Concentrations After Storage
Average within‐tube bias (%) for BD serum glass (95% confidence interval) | Average within‐tube bias (%) for BD SST™ II plus (95% confidence interval) | ||||||||
---|---|---|---|---|---|---|---|---|---|
Analytes | n | t 8–t 0 | t 24–t 0 | t 48–t 0 | t 72–t 0 | t 8–t 0 | t 24–t 0 | t 48–t 0 | t 72–t 0 |
AFP | 30 | −0.5 | 0.1 | 0.2 | −0.3 | −0.4 | −0.2 | 0.2 | −0.1 |
(ng/ml) | (−1.1, 0.1) | (−0.3, 0.6) | (−0.8, 1.1) | (−1.0, 0.4) | (−0.9, 0.1) | (−0.7, 0.3) | (−0.7, 1.2) | (−0.8, 0.7) | |
CEA | 30 | 0.0 | 0.1 | 0.1 | −0.1 | 0.2 | 0.1 | −0.1 | 0.1 |
(ng/ml) | (−0.4, 0.4) | (−0.6, 0.8) | (0.0, 0.2) | (−1.5, 1.3) | (−0.4, 0.7) | (−0.2, 0.3) | (−0.4, 0.2) | (−1.1, 1.3) | |
CA19‐9 | 30 | 0.3 | 0.2 | −0.1 | −0.4 | 0.2 | −0.3 | −0.7 | 0.0 |
(U/ml) | (−0.1, 0.7) | (−1.0, 1.3) | (−0.8, 0.6) | (−1.2, 0.4) | (0.1, 0.3) | (−0.7, 0.1) | (−1.2, −0.2) | (−0.7, 0.6) | |
CA125 | 30 | 0.8 | 1.1 | 0.0 | −0.3 | −0.1 | 0.9 | 0.5 | 0.7 |
(U/ml) | (−0.2, 1.8) | (0.2, 2.0) | (−1.0, 1.0) | (−1.2, 0.7) | (−1.4, 1.2) | (−1.2, 2.9) | (−1.4, 2.3) | (−0.1, 1.4) | |
CA15‐3 | 30 | 1.0 | 0.4 | −0.2 | 0.7 | 0.2 | −0.3 | −0.7 | 0.6 |
(U/ml) | (−0.3, 2.2) | (−0.4, 1.2) | (−1.5, 1.1) | (−0.5, 1.9) | (0.1, 0.3) | (−0.7, 0.1) | (−1.2, −0.2) | (−0.3, 1.5) | |
TPSA | 30 | 1.3 | 0.2 | 0.5 | −0.1 | 0.6 | 1.5 | 0.7 | 0.8 |
(ng/ml) | (−0.1, 2.7) | (−0.4, 0.9) | (−0.8, 1.8) | (−0.2, 0.1) | (−0.3, 1.6) | (0.4, 2.6) | (−0.3, 1.7) | (−0.5, 2.1) | |
FPSA | 30 | 0.3 | 0.9 | 0.1 | 1.4 | 0.7 | −0.2 | 0.8 | 1.1 |
(ng/ml) | (−0.2, 0.8) | (−0.4, 2.1) | (−0.5, 0.7) | (−0.2, 3.0) | (0.1, 1.3) | (−0.6, 0.2) | (−1.0, 2.6) | (−0.5, 2.7) | |
NSE | 30 | 4.6 | 9.2 | 12.5 | 19.7 | −0.9 | 0.2 | 1.6 | 1.2 |
(ng/ml) | (2.1, 7.0) | (2.8, 15.6) | (4.6, 20.5) | (8.8, 30.6) | (−2.2, 0.4) | (−0.6, 1.0) | (0.3, 2.9) | (−0.2, 2.6) | |
CYFRA21‐1 | 30 | 0.6 | 1.0 | 0.4 | 0.0 | 1.2 | 0.3 | −0.2 | 0.6 |
(ng/ml) | (−0.4, 1.7) | (−0.2, 2.2) | (−0.8, 1.6) | (−1.2, 1.2) | (0.2, 2.2) | (−0.4, 1.0) | (−0.7, 0.3) | (−0.2, 1.4) | |
CA72‐4 | 30 | 0.1 | 0.7 | −0.2 | −0.4 | 1.4 | 0.5 | 0.7 | 0.2 |
(U/ml) | (−1.1, 1.3) | (−0.5, 1.9) | (−0.6, 0.2) | (−1.5, 0.7) | (0.3, 2.5) | (−1.2, 2.2) | (−1.5, 2.9) | (−0.4, 0.8) |