Table 2.
Paraoxonase1 and XO Activities and Their Concentration in Human Plasma of Normal Healthy Persons and Cardiac Patients
| Enzyme activity and concentration | ||||||
|---|---|---|---|---|---|---|
| Subjects | Age (years) | PON activity (nmol/ml/min) | ARY activity (nmol/ml/min) | XO activity (U/ml) | PON1 conc (µg/ml) | XO conc. (µg/ml) |
| Normal persons (n=200) | ||||||
| (Group I‐A) (n=60) | 42.50±13.22 | 89±39.16 | 51±10.87 | 0.015±0.07 | 79.5±1.55 | 0.62±0.29 |
| (Group I‐B) (n=140) | 40.23±05.12 | 91±38.32 | 53±11.07 | 0.013±0.09 | 81.5±2.36 | 0.60±0.19 |
| Cardiac patients (n=200) | ||||||
| Admitted in ICU (n=60) | ||||||
| (Group II) | 42.50±10.86 | 71±8.14 | 38.40±3.36 | 0.11±0.04 | 57±1.7 | 1.82±0.20a |
| Hypertensive (n=140) | ||||||
| (Group III) | 40.50±4.20 | 83±38.08 | 49.50±9.54 | 0.081±0.05 | 64±1.25 | 0.92±0.14a |
Values are presented as mean±SD. PON (Paraoxonase), ARY (Arylesterase), XO (Xanthine oxidase), PON1 (Paraoxonase1).
a
aElevated levels of activity and concentration of XO enzyme and low levels of activity and concentration of PON1 enzyme were observed.