Table 3.
Genotypes and Allele Frequencies of T102C Polymorphism in 5HTR2A Gene in NE Children Presented With Different Phenotypes
DVS | High arousal score | Constipation | |||||||
---|---|---|---|---|---|---|---|---|---|
No. patients | Yes (n=48) | No (n=57) | Odds ratio (95% CI) | Yes (n=54) | No (n=62) | Odds ratio (95% CI) | Yes (n=37) | No (n=68) | Odds ratio (95% CI) |
Genotype | |||||||||
TT | 30 | 14 | 10.71 (2.66,43.12) | 25 | 25 | 1.5 (0.52,4.30) | 27 | 17 | 12.71 (2.59,62.33) |
TC | 15 | 28 | 2.68 (0.67,10.75) | 21 | 25 | 1.26 (0.43,3.66) | 8 | 35 | 1.83 (0.35,9.6) |
CC | 3 | 15 | 1 | 8 | 12 | 1 | 2 | 16 | 1 |
P=0.0002 | P=0.74 | P=0.00001 | |||||||
Allelic frequency | |||||||||
T | 75 | 56 | 3.7 (2.01,6.79) | 71 | 75 | 1.25 (0.73,2.14) | 62 | 69 | 5.02 (2.48,10.14) |
C | 21 | 58 | 1 | 37 | 49 | 1 | 12 | 67 | 1 |
P=0.000015 | P=0.41 | P=0.000002 |
The Pearson χ2 test was performed to obtain the P value. A P value of <0.05 was considered as statistically significant. Patient numbers may not add up to 116 because of some clinical data are missing.