Table 6.
The Risk of Hyperhomocysteinemia According to Various Physiologic and Lifestyle Factors in a Korean Population
| Variable | Hyperhomocyteinemiaa | Adjusted OR (95% CI) | P‐value |
|---|---|---|---|
| Age, yrs | |||
| 20–39 | 15/109 (13.8) | 1 (Ref) | |
| 40–59 | 19/202 (8.6) | 0.688 (0.294–1.612) | 0.390 |
| 60–79 | 3/26 (11.5) | 0.473 (0.051–4.355) | 0.508 |
| P for trend | 0.305 | ||
| Gender | |||
| Male | 32/204 (15.7) | 5.705 (1.568–20.761) | 0.008 |
| Female | 5/152 (3.3) | 1 (Ref) | |
| Folate level | |||
| Low | 23/116 (19.8) | 10.412 (2.326–46.606) | 0.002 |
| Medium | 6/64 (9.4) | 5.163 (0.987–27.013) | 0.052 |
| High | 2/124 (1.6) | 1 (Ref) | |
| P for trend | 0.000 | ||
| Smoking | |||
| Yes | 12/79 (15.2) | 1.156 (0.493–2.712) | 0.739 |
| No | 20/227 (8.8) | 1 (Ref) | |
| Regular exercise | |||
| Yes | 17/179 (9.5) | 1 (Ref) | |
| No | 15/128 (11.7) | 1.551 (0.663–3.630) | 0.311 |
| Vitamin supplement | |||
| Use | 5/89 (5.6) | 1 (Ref) | |
| Nonuse | 28/219 (12.8) | 1.656 (0.574–4.772) | 0.351 |
Multivariate logistic regression analysis was used for the statistical analysis. OR, odds ratio; CI, confidence interval.
a
aHyperhomocyteinemia was defined as a serum homocysteine level ≥15 μmol/l.