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. 2010 Sep 20;24(5):289–294. doi: 10.1002/jcla.20402

Table 1.

Accuracy and Reliability of an Enzyme Immunoassay (ELISA) for the Diagnosis of American Tegumentary Leishmaniasis Using Soluble and Membrane‐Enriched Fractions Obtained From Infectious L. (Viannia) braziliensis (N=152)

Parameter Soluble fraction Enriched membrane fraction
Cutoff 0.22 0.33
AUCa 0.918 (80.3–95.5) 0.934 (88.2–96.8)
Sensitivity 89.5 (80.6–95.3) 89.5 (80.3–95.3)
Specificity 89.5 (80.3–95.3) 93.4 (85.3–97.8)
Positive preditive value 89.5 (81.7–94.2) 93.2 (85.8–96.9)
Negative preditive Value 89.5 (81.8–94.2) 89.9 (82.4–94.4)
LRb positive 8.5 (4.4–16.5) 13.6 (5.8–31.8)
LR negative 0.12 (0.06–0.23) 0.11(0.06–0.22)
ICCc 0.96 (94.1–96.8) 0.90 (85.9–92.3)
a

aArea under the curve.

b

bLikelihood ratio.

c

cIntraclass correlation coefficient.