Table 1.
Accuracy and Reliability of an Enzyme Immunoassay (ELISA) for the Diagnosis of American Tegumentary Leishmaniasis Using Soluble and Membrane‐Enriched Fractions Obtained From Infectious L. (Viannia) braziliensis (N=152)
| Parameter | Soluble fraction | Enriched membrane fraction |
|---|---|---|
| Cutoff | 0.22 | 0.33 |
| AUCa | 0.918 (80.3–95.5) | 0.934 (88.2–96.8) |
| Sensitivity | 89.5 (80.6–95.3) | 89.5 (80.3–95.3) |
| Specificity | 89.5 (80.3–95.3) | 93.4 (85.3–97.8) |
| Positive preditive value | 89.5 (81.7–94.2) | 93.2 (85.8–96.9) |
| Negative preditive Value | 89.5 (81.8–94.2) | 89.9 (82.4–94.4) |
| LRb positive | 8.5 (4.4–16.5) | 13.6 (5.8–31.8) |
| LR negative | 0.12 (0.06–0.23) | 0.11(0.06–0.22) |
| ICCc | 0.96 (94.1–96.8) | 0.90 (85.9–92.3) |
aArea under the curve.
bLikelihood ratio.
cIntraclass correlation coefficient.