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. 2019 Mar 11;23(8):987–994. doi: 10.1007/s10157-019-01719-4

Fig. 9.

Fig. 9

SGLT2 is involved in PT (proximal tubules)-Pod (podocyte) communication. Augmented SGLT2 expression diminishes SIRT1 expression, which is blocked by a SGLT2 inhibitor. SGLT2 sodium-glucose cotransporter-2