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. Author manuscript; available in PMC: 2019 Jul 23.
Published in final edited form as: Biochem J. 2019 Mar 12;476(5):859–873. doi: 10.1042/BCJ20180916

Figure 7. Reduction in GRN-3 induces augmentation in fibril formation.

Figure 7

Incubation of 40 μM GRN-3 with 20 μM Aβ42 at 37°C was monitored using turbidity measurements at 360 nm (A) or by ThT assay (B). After 2 h of incubation, the reaction was reduced by the addition of 500 μM TCEP (arrow) to observe the subsequent kinetics (∇; Ox → Red). Reactions with rGRN-3 (■) and GRN-3 (○) were used as reaction controls along with others such as Aβ (♦), rAβ (⬡), rGRN-3 (✳), and GRN-3 (♦).