Skip to main content
. Author manuscript; available in PMC: 2019 Jul 23.
Published in final edited form as: AAPS J. 2019 Feb 13;21(2):30. doi: 10.1208/s12248-019-0303-4

Fig. 2. Effect of PKA activator Bt2-cAMP on the kinetics of hOAT3-mediated transport of estrone sulfate.

Fig. 2.

hOAT3-expressing cells were treated with the Bt2-cAMP (10μM, 30min), and initial uptake (4 min) of [3H] estrone sulfate was determined at the concentration of 0.1–10 μM. The data correspond to uptake into hOAT3-expressing cells minus uptake into mock cells. Values are means ± S.D. (n = 3). V, velocity; S, substrate concentration.