Table 2.

Kinetic of humoral response (anti-rtTA, anti-AAV1 responses, and anti-AAV1 neutralizing factors

		Before injection	15 days post injection	3 months post injection	10 months post injection	2.5 years post injection	5 years post injection
Mac 19	Anti-AAV1 Ab	Negative	1/40	1/10,240	1/10,240	1/5,120	1/5,120
	Anti-AAV1 NF	Negative	ND	1/5,000	ND	ND	1/1,000
	Anti-rtTA Ab	Negative	Negative	Negative	Negative	Negative	Negative
Mac 20	Anti-AAV1 Ab	Negative	1/80	1/5,120	1/1,280	1/320	1/80
	Anti-AAV1 NF	Negative	ND	1/1,000	ND	ND	1/100
	Anti-rtTA Ab	Negative	Negative	Negative	Negative	Negative	Negative
Mac 21	Anti-AAV1 Ab	Negative	1/80	1/10,240	1/10,240	1/5,120	1/1,280
	Anti-AAV1 NF	Negative	ND	1/5,000	ND	ND	1/1,000
	Anti-rtTA Ab	Negative	Negative	Negative	Negative	Negative	Negative

ND, not determined; NF, neutralizing factors.