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. 2019 Jul 17;29(7):934–945. doi: 10.1089/thy.2018.0709

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© Julieta Fernandez-Ruocco et al. 2019; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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FIG. 4. — TSH modulation of Ca²⁺ and K⁺ currents in myocytes from control animals and rats with either central or primary hypothyroidism. (A) Incubation for 24 hours with 30 mIU/L of TSH did not affect I_Ca-L in any of the experimental groups (n = 8–9 cells from three different animals in each group). (B) Incubation with TSH reduced the I_to amplitude in the control and central hypothyroid groups, but had no effect in the primary hypothyroidism group. Means ± SEM. n = 10–13 cells from at least three different animals in each group. Dashed lines represent the 0 current level. *p < 0.05; **p < 0.01.