Table 1. Optimization of GNPs Using the D-Optimal Experimental Design.

run	GA %	CLT (h)	stirring speed (rpm)	mean P.S. (nm) ± SD	mean PDI ± SD
1	33.30	16.00	1000.00	786.1 ± 100.4	0.1785 ± 0.005
2	66.70	16.00	700.00	629.75 ± 4.74	0.307 ± 0.034
3	66.70	4.00	700.00	389.85 ± 2.89	0.057 ± 0.033
4	50.00	7.00	1150.00	402.22 ± 2.83	0.1635 ± 0.013
5	33.30	4.00	1000.00	663.55 ± 8.69	0.535 ± 0.069
6	33.30	16.00	700.00	740.45 ± 1.2	0.3645 ± 0.036
7	66.70	16.00	1300.00	566.7 ± 0.14	0.2515 ± 0.043
8	66.70	16.00	700.00	622.4 ± 0.85	0.1115 ± 0.153
9	50.00	10.00	850.00	416.84 ± 8.88	0.3215 ± 0.027
10	33.30	4.00	1300.00	431.5 ± 2.12	0.148 ± 0.132
11	33.30	10.00	1300.00	385.5 ± 21.25	0.3895 ± 0.062
12	66.70	4.00	700.00	370.7 ± 6.78	0.0363 ± 0.009
13	33.30	4.00	700.00	478.25 ± 3.04	0.473 ± 0.0255
14	50.00	16.00	1300.00	378.8 ± 1.55	0.122 ± 0.029
15	66.70	4.00	1300.00	547.65 ± 12.79	0.129 ± 0.0594
16	33.30	10.00	1300.00	388 ± 2.98	0.405 ± 0.064