Table 1. Optimization of the One-Pot RCM/Oxidation/1,3-Dipolar Cycloaddition Protocol.

		RCM				1,3-dipolar cycloaddition			isolated yield
entry	Grubbs II (mol %)	solvent	temp. (°C)	conc. (M)	time (min)	temp. (°C)	conc. (M)	time (min)	(%, two steps)
1	10	benzene	reflux	0.01	30	reflux	0.01	60	15
2	20	benzene	reflux	0.01	30	reflux	0.01	60	11
3	5	benzene	reflux	0.01	30	reflux	0.01	60	16
4	1	benzene	reflux	0.01	30	reflux	0.01	60	18
5	1	toluene	80	0.01	30	80	0.01	60	18
6	1	toluene	80	0.01	10	80	0.01	30	18
7a	1	toluene	80	0.1	10	80	0.1	30	5
8b	1	toluene	80	0.01	10	80	0.01	30	15

^aCross metathesis product was also isolated in 28% yield.

^bReaction was performed in a glovebox.