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Biophysical analysis of the dioxygenases. (a) Structural alignment of KaPH1 and P4H. The model of KaPH1 and P4H is displayed in purple and green, respectively. Molecular docking results of 2-OG and substrate l-proline in (b) KaPH1 and (c) P4H. The distances between C4 of l-proline/C1 of 2-OG and Fe(II) are illustrated by yellow dashed lines.
