Table 2. Solubilities of Glycine in Water and Organic Solvents, as log C, and Water–Solvent Partition Coefficients, as log P, at 298 K.
| log P |
|||||
|---|---|---|---|---|---|
| solvent | log C | refs | obsa | taken | calc |
| water | 0.460 | (32) | |||
| water | 0.462 | (33, 34) | |||
| water | 0.522 | (35) | |||
| water | 0.522 | (36) | |||
| water | 0.460 | (37, 38) | |||
| water | 0.497 | (39) | |||
| methanol | –2.045 | (34) | –2.535 | –2.66 | –2.18 |
| methanol | –1.939 | (36) | –2.429 | ||
| methanol | –2.370 | (38) | –2.860 | ||
| methanol | –2.345 | (40) | –2.835 | ||
| ethanol | –2.400 | (34) | –2.890 | –3.31 | –3.15 |
| ethanol | –2.071 | (36) | –2.561 | ||
| ethanol | –3.409 | (38) | –3.899 | ||
| ethanol | –3.026 | (39) | –3.516 | ||
| ethanol | –3.188 | (40) | –3.678 | ||
| propan-1-ol | –1.959 | (34) | –2.449 | –3.30 | –3.34 |
| propan-1-ol | –2.826 | (39) | –3.316 | ||
| propan-1-ol | –3.638 | (40) | –4.128 | ||
| propan-2-ol | –4.824 | (36) | –5.314 | –3.55 | –3.89 |
| propan-2-ol | –2.400 | (34) | –2.890 | ||
| propan-2-ol | –3.030 | (39) | –3.520 | ||
| propan-2-ol | –3.745 | (34) | –4.235 | ||
| butan-1-ol | –4.018 | (38) | –4.508 | –4.45b | –3.78b |
| butan-1-ol | –3.921 | (40) | –4.411 | ||
| tert-butanol | –2.400 | (34) | –2.890 | –4.25 | –4.12 |
| tert-butanol | –4.886 | (35) | –5.376 | ||
| tert-butanol | –4.000 | (40) | –4.490 | ||
| ethylene glycol | –0.711 | (41) | –1.201 | –1.20 | –1.40 |
| ethylene glycol | –0.709 | (42) | –1.199 | ||
| DMSO | –1.338 | (41) | –1.828 | –1.83 | –1.34 |
| dioxane | –2.710 | (43) | –3.200 | –3.20 | |
| acetonitrile | –1.453 | (42) | –1.943 | –1.94 | –1.83 |
| propanone | –4.516 | (38) | –5.006 | –5.01b | –2.48b |
| formamide | –1.077 | (38) | –1.567 | –1.57 | –1.46 |
| dimethylformamide | –1.362 | (44) | –1.852 | –1.85 | –2.49 |
| 2-methoxyethanol | –0.627 | (45) | –1.117 | –1.12 | |
| 1,2-dimethoxyethane | –0.728 | (46) | –1.218 | –1.22 | |
| octan-1-ol, wet | (2) | –3.21c | –3.21 | –3.34 | |
| butan-1-ol, wet | (2, 32) | –1.81c | –1.81 | –1.76 | |
a
With log C in water taken as 0.490.
b
Not used in the calculations.
c
Direct determination.