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. Author manuscript; available in PMC: 2019 Jul 23.
Published in final edited form as: Cancer Cell. 2018 Jun 11;33(6):1017–1032.e7. doi: 10.1016/j.ccell.2018.05.009

Table 1. Post-therapy 4PD1hi and clinical benefit of pembrolizumab.

Hazard ratios (risk of death) for post-therapy 4PD1hi% and 4PD1hi fold reduction by the Cox regression model in advanced melanoma patients treated with pembrolizumab (Figure 4C).

Variable n Hazard Ratio 95% CI Cox p value
4PD1hi % (3 weeks post-therapy) 52 (24 deaths) 1.4 (1.16, 1.70) .0005 ***
FoldChange in 4PD1hi% 52 (24 deaths) 4.4 (1.03, 19.14) .046 *