Table 1.
Patient demographics of cervical cancer (N=6,359)
| Trachelectomy | Hysterectomy | P-value | |
|---|---|---|---|
| Characteristic | n=190 | n=6,169 | |
| Age (years) | 31.0 (28–34) | 37.0 (33–41) | <0.001 |
| ≥ 40 | 13 (6.8%) | 2,175 (35.3%) | |
| < 40 | 177 (93.2%) | 3,994 (64.7%) | |
| Race/ethnicity | 0.02 | ||
| White | 122 (64.2%) | 3,654 (59.2%) | |
| Black | 5 (2.6%) | 554 (9.0%) | |
| Hispanic | 50 (26.3%) | 1,458 (23.6%) | |
| Others | 13 (6.8%) | 503 (8.2%) | |
| Marital status | <0.001 | ||
| Single | 93 (48.9%) | 1,656 (26.8%) | |
| Married | 79 (41.6%) | 3,487 (56.5%) | |
| Others | 18 (9.5%) | 1,026 (16.6%) | |
| Registry area | 0.004 | ||
| West | 104 (54.7%) | 3,507 (60.7%) | |
| Central | 25 (13.2%) | 1,243 (21.5%) | |
| East | 61 (32.1%) | 1,419 (17.8%) | |
| Year at diagnosis | <0.001 | ||
| 1998–2002 | 23 (12.1%) | 1,844 (29.9%) | |
| 2003–2008 | 72 (37.9%) | 2,313 (37.5%) | |
| 2009–2014 | 95 (50.0%) | 2,012 (32.6%) | |
| Stage | <0.001 | ||
| IA1 | 43 (22.6%) | 2,696 (43.7%) | |
| IA2 | 47 (24.7%) | 1,330 (21.6%) | |
| IA NOS | 2 (1.1%) | 114 (1.8%) | |
| IB1 | 98 (51.6%) | 2,029 (32.9%) | |
| Histology | <0.001 | ||
| Squamous | 92 (48.4%) | 4,062 (65.8%) | |
| Adenocarcinoma | 86 (45.3%) | 1,863 (30.2%) | |
| Adenosquamous | 12 (6.3%) | 244 (4.0%) | |
| Grade | 0.001 | ||
| 1 | 38 (20.0%) | 1,138 (18.4%) | |
| 2 | 76 (40.0%) | 1,836 (29.8%) | |
| 3* | 31 (16.3%) | 875 (14.2%) | |
| Unknown | 45 (23.7%) | 2,320 (37.6%) | |
| Pelvic lymphadenectomy** | <0.001 | ||
| No | 17 (8.9%) | 2,429 (39.5%) | |
| Yes | 173 (91.1%) | 3,728 (60.5%) | |
| Surgery type | |||
| Trachelectomy | 190 (100%) | - | |
| Total hysterectomy | - | 3,200 (51.9%) | |
| Extended, mRH, RH | - | 2,544 (41.2%) | |
| Hysterectomy, NOS | - | 425 (6.9%) | |
| Adjuvant radiotherapy | 0.33 | ||
| None | 183 (96.3%) | 5,795 (93.9%) | |
| WPRT ± VBT | 6 (3.2%) | 349 (5.7%) | |
| RT NOS | 1 (0.5%) | 25 (0.5%) | |
| Adjuvant chemotherapy | 0.50 | ||
| None/unknown | 185 (97.4%) | 5,984 (97.0%) | |
| performed | 5 (2.6%) | 185 (3.0%) |
Number (% per column) or median (interquartile range) is shown. Univariable analysis for P-values. Significant P-values are emboldened.
*
included high-grade tumors.
**
excluding 12 cases unknown lymphadenectomy status.
Abbreviations: NOS, not otherwise specified; mRH, modified radical hysterectomy; RH, radical hysterectomy; WPRT, whole pelvic radiotherapy; VBT, vaginal brachytherapy; and RT, radiotherapy.