. 2019 Jul 16;10:1582. doi: 10.3389/fimmu.2019.01582

Table 2.

Phenotypic and functional characteristics of human liver-resident NK cells and other tissue-resident NK cells.

		Surface markers	Transcription factors	Effector molecules
Liver	CD49a⁺	CD56^brightCD49a⁺CD69⁺CD103⁺ CXCR6⁻	T-bet^hiEomes^lo/−	IFN-γ⁺TNF-α⁺GM-CSF⁺ CD107a⁺Perforin⁺Granzyme⁺
	Eomes^hi	CD56^brightCD49a⁻ CD69⁺ CD103⁻ CXCR6⁺	T-bet^loEomes^hi	IFN-γ⁺TNF-α⁺GM-CSF⁺ CD107a⁺Perforin^loGranzyme^lo
	CD49e⁻	CD56^bright CD69⁺ CXCR6⁺	T-bet⁺Eomes^hi	IFN-γ⁺ TNF-α⁺ CD107a⁺
Uterus		CD56^brightCD49a⁺CD103^+/− CD69^+/−	Eomes⁺	IFN-γ⁺TNF-α⁺GM-CSF⁺ Perforin⁺ Granzyme⁺
Tonsil		CD56^brightCD49a⁺CD69⁺ CD103⁺ CXCR6⁺integrinβ7⁺	T-bet⁺Eomes⁺	IFN-γ⁺CD107a⁺Perforin⁺ Granzyme⁺
Lung		CD56^brightCD49a⁺CD69⁺ CD103⁺ CXCR3⁺	ND	IFN-γ⁺CD107a⁺ Granzyme⁺
Lymphoid tissue		CD56^brightCD49a⁻ CD69⁺ CD103⁻ CXCR6⁺	Eomes⁺	IFN-γ^loCD107a⁺Perforin⁺ Granzyme^lo

ND, not determined.