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. 2019 Jun 10;4(6):10056–10069. doi: 10.1021/acsomega.9b00640

Figure 11.

Figure 11

Representative nonsymmetrical compounds 37, 40, 43, and 48. The terminal carboxylates, phenoxy moiety, and core were substituted. Four compounds among the 15 synthesized and assayed are shown. None among the 15 nonsymmetrical compounds inhibited DfrB1 (Tables S6 and S7).